Prostate Specific Antigen, Total
tPSA
Testing Information
Sample Type
Serum
Test Codes
630350
CPT Code
84153
Testing Area
Core Lab - Chemistry
Test Methodology
Abbott Alinity - Chemiluminescence Immunoassay
Reference Range
<4.0 ng/mL
Expected Turnaround Time
Results Available 24 hours from Receipt
Specimen Collection Criteria
Collect one gold top SST tube (minimum whole blood: 4 mL). Let specimen clot for 30-60 minutes and then centrifuge to separate serum from cells. Refrigerate after centrifugation.
Rejection Criteria
Grossly hemolyzed specimens, female patients, quantity not sufficient, improperly labeled
Specimen Validity and Retention
Centrifuged SST Tubes:Room Temperature (20-25°C): 8 hoursRefrigerated (2-8°C): 5 daysFrozen (-20°C or greater): UnacceptableSerum Aliquots:Room Temperature (20-25°C): 8 hoursRefrigerated (2-8°C): 5 daysFrozen (-20°C or greater): 7 daysSpecimens retained for 7 days after testing
Courier Transportation
Transport centrifuged tube refrigerated (2-8°C)
Clinical Utility
Total PSA tests are frequently used to monitor those with a history of prostate cancer. It is also recommended by the American Cancer Society to utilize as a screening test starting at age 50, although there are exceptions for at risk populations.
